The objective of this project is to establish a pathological and genetic classification and grading of human tumours that is accepted and used worldwide. Without clearly defined clinical and histopathological diagnostic criteria and, more recently, genetic and expression profiles, epidemiological studies and clinical trials are difficult to conduct. This project therefore has a substantial impact in not only pathology communities, but also cancer registration, epidemiology studies, clinical trials, and cancer research in general.

IARC has been responsible for this book project since the 3rd edition (2000–2005), which covered all organ sites in 10 volumes. Diagnostic criteria, pathological features and associated genetic alterations were described in a strictly disease-oriented manner. For each volume, 10 000–35 000 copies were printed and distributed worldwide.

The Section of Molecular Pathology at IARC is responsible for the publication of the 4th edition of the WHO/IARC Classification of Tumours series.


WHO/IARC Classification of Tumours - News


IARC Publications: WHO Classification of Tumours of the Central Nervous System

WHO Classification of Tumours of the Central Nervous System WHO/IARC Classification of Tumours, 4th Edition Revised, Volume 1
Edited by Louis DN, Ohgaki H, Wiestler OD, Cavenee WK.

WHO Classification of Tumours of the Central Nervous System is the Revised 4th Edition of the WHO series on histological and genetic typing of human tumours. Diagnostic criteria, pathological features, and associated genetic alterations are described in a disease-oriented manner. Sections on all recognized neoplasms and their variants include new ICD-O codes, epidemiology, clinical features, macroscopy, pathology, genetics, and prognosis and predictive factors.
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