Thoracic Tumours

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Tumours of the lung

    Tumours of the lung: Introduction

    Small diagnostic samples

    Epithelial tumours

         Papillomas
              Bronchial papillomas
         Adenomas
              Sclerosing pneumocytoma
              Alveolar adenoma
              Papillary adenoma of the lung
              Bronchiolar adenoma / ciliated muconodular papillary tumour
              Mucinous cystadenoma of the lung
              Mucous gland adenoma of the lung
         Precursor glandular lesions
              Atypical adenomatous hyperplasia of the lung
              Adenocarcinoma in situ of the lung
         Adenocarcinomas
              Minimally invasive adenocarcinoma of the lung
              Invasive non-mucinous adenocarcinoma of the lung
              Invasive mucinous adenocarcinoma of the lung
              Colloid adenocarcinoma of the lung
              Fetal adenocarcinoma of the lung
              Enteric-type adenocarcinoma of the lung
         Squamous precursor lesions
              Squamous dysplasia and carcinoma in situ of the lung
         Squamous cell carcinomas
              Squamous cell carcinoma of the lung
              Lymphoepithelial carcinoma of the lung
         Large cell carcinomas
              Large cell carcinoma of the lung
         Adenosquamous carcinoma
              Adenosquamous carcinoma of the lung
         Sarcomatoid carcinomas
              Pleomorphic carcinoma of the lung
              Pulmonary blastoma
              Carcinosarcoma of the lung
         Other epithelial tumours
              NUT carcinoma of the lung (see NUT carcinoma of the thorax)
              Thoracic SMARCA4-deficient undifferentiated tumour
         Salivary gland-type tumours
              Pleomorphic adenoma of the lung
              Adenoid cystic carcinoma of the lung
              Epithelial-myoepithelial carcinoma of the lung
              Mucoepidermoid carcinoma of the lung
              Hyalinizing clear cell carcinoma of the lung
              Myoepithelioma and myoepithelial carcinoma of the lung

    Lung neuroendocrine neoplasms

         Lung neuroendocrine neoplasms: Introduction
         Precursor lesion
              Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia
         Neuroendocrine tumours
              Carcinoid/neuroendocrine tumour of the lung
         Neuroendocrine carcinomas
              Small cell lung carcinoma
              Large cell neuroendocrine carcinoma of the lung

    Tumours of ectopic tissues

              Melanoma of the lung
              Meningioma of the lung

    Mesenchymal tumours specific to the lung

              Pulmonary hamartoma
              Pulmonary chondroma
              Diffuse pulmonary lymphangiomatosis
              Pleuropulmonary blastoma
              Pulmonary artery intimal sarcoma
              Congenital peribronchial myofibroblastic tumour
              Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion
         PEComatous tumours
              Lymphangioleiomyomatosis of the lung
              PEComa of the lung

    Haematolymphoid tumours

              Haematolymphoid tumours of the lung: Introduction
              MALT lymphoma of the lung
              Pulmonary diffuse large B-cell lymphoma
              Lymphomatoid granulomatosis of the lung
              Intravascular large B-cell lymphoma of the lung
              Pulmonary Langerhans cell histiocytosis
              Pulmonary Erdheim-Chester disease

Tumours of the pleura and pericardium

    Tumours of the pleura and pericardium: Introduction

    Mesothelial tumours

         Benign and preinvasive mesothelial tumours
              Adenomatoid tumour of the pleura
              Well-differentiated papillary mesothelial tumour of the pleura
              Mesothelioma in situ
         Mesothelioma
              Localized pleural mesothelioma
              Diffuse pleural mesothelioma

    Haematolymphoid tumours

              Haematolymphoid tumours of the pleura and pericardium: Introduction
              Primary effusion lymphoma
              Diffuse large B-cell lymphoma associated with chronic inflammation of the pleura

Tumours of the heart

    Tumours of the heart: Introduction

    Benign tumours

              Papillary fibroelastoma
              Cardiac myxoma
              Cardiac fibroma
              Cardiac rhabdomyoma
              Adult cellular rhabdomyoma
              Cardiac lipoma and lipomatous hypertrophy of the atrial septum
              Lipomatous hamartoma of the atrioventricular valve
              Hamartoma of mature cardiac myocytes
              Mesenchymal cardiac hamartoma
              Cardiac haemangiomas
              Conduction system hamartoma
              Cystic tumour of the atrioventricular node

    Malignant tumours

              Cardiac angiosarcoma
              Cardiac leiomyosarcoma
              Cardiac undifferentiated pleomorphic sarcoma
              Other sarcomas that may involve the heart

    Haematolymphoid tumours

              Haematolymphoid tumours of the heart: Introduction
              Cardiac diffuse large B-cell lymphoma
              Cardiac fibrin-associated diffuse large B-cell lymphoma

Mesenchymal tumours of the thorax

    Mesenchymal tumours of the thorax: Introduction

    Mesenchymal tumours

         Adipocytic tumours
              Lipoma of the thorax
              Thymolipoma
              Liposarcoma of the thorax
         Fibroblastic and myofibroblastic tumours
              Desmoid fibromatosis of the thorax
              Solitary fibrous tumour of the thorax
              Calcifying fibrous tumour of the thorax
              Inflammatory myofibroblastic tumour of the thorax
              Myxofibrosarcoma of the thorax
         Vascular tumours
              Haemangioma of the thorax
              Lymphangioma of the thorax
              Epithelioid haemangioendothelioma of the thorax
              Angiosarcoma of the thorax
         Skeletal muscle tumours
              Rhabdomyosarcoma of the thorax
         Peripheral nerve sheath and neural tumours
              Paraganglioma of the thorax
              Granular cell tumour of the thorax
              Schwannoma of the thorax
              Malignant peripheral nerve sheath tumour of the thorax
              Peripheral neuroblastic tumours of the thorax
         Tumours of uncertain differentiation
              Synovial sarcoma of the thorax
              Undifferentiated small round cell sarcomas of the thorax

Tumours of the thymus

    Epithelial tumours

         Thymoma
         Thymoma: Introduction
              Type A thymoma (including atypical subtype)
              Type AB thymoma
              Type B1 thymoma
              Type B2 thymoma
              Type B3 thymoma
              Micronodular thymoma with lymphoid stroma
              Metaplastic thymoma
              Lipofibroadenoma of the thymus
         Thymic carcinoma: Introduction
              Squamous cell carcinoma of the thymus
              Basaloid carcinoma of the thymus
              Lymphoepithelial carcinoma of the thymus
              NUT carcinoma of the thorax
              Clear cell carcinoma of the thymus
              Low-grade papillary adenocarcinoma of the thymus
              Mucoepidermoid carcinoma of the thymus
              Thymic carcinoma with adenoid cystic carcinoma-like features
              Enteric-type adenocarcinoma of the thymus
              Adenocarcinoma NOS of the thymus
              Adenosquamous carcinoma of the thymus
              Sarcomatoid carcinoma of the thymus
              Undifferentiated carcinoma of the thymus
              Thymic carcinoma NOS

    Thymic neuroendocrine neoplasms

         Thymic neuroendocrine neoplasms: Introduction
         Neuroendocrine tumours
              Carcinoid/neuroendocrine tumour of the thymus
         Neuroendocrine carcinomas
              Small cell carcinoma of the thymus
              Large cell neuroendocrine carcinoma of the thymus

Germ cell tumours of the mediastinum

         Germ cell tumours of the mediastinum: Introduction
              Seminoma of the mediastinum
              Embryonal carcinoma of the mediastinum
              Yolk sac tumour of the mediastinum
              Choriocarcinoma of the mediastinum
              Teratoma of the mediastinum
              Mixed germ cell tumours of the mediastinum
              Mediastinal germ cell tumours with somatic-type solid malignancy
              Mediastinal germ cell tumours with associated haematological malignancy

Haematolymphoid tumours of the mediastinum

              Haematolymphoid tumours of the mediastinum: Introduction
              Primary mediastinal large B-cell lymphoma
              MALT lymphoma of the mediastinum
              Mediastinal T-lymphoblastic leukaemia/lymphoma
              Classic Hodgkin lymphoma of the mediastinum
              Mediastinal grey zone lymphoma
              Follicular dendritic cell sarcoma of the mediastinum
              Myeloid sarcoma of the mediastinum

Ectopic tumours of thyroid and parathyroid origin

              Ectopic thyroid tumours
              Ectopic parathyroid tumours

Metastases

              Metastasis to the lung
              Metastasis to the pleura
              Metastasis to the thymus and mediastinal lymph nodes
              Metastasis to the heart and pericardium

Genetic tumour syndromes involving the thorax

         Genetic tumour syndromes involving the thorax: Introduction
              Li-Fraumeni syndrome
              BAP1 tumour predisposition syndrome
              Carney complex

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