Central Nervous System Tumours

Gliomas, glioneuronal tumours, and neuronal tumours

              Gliomas, glioneuronal tumours, and neuronal tumours: Introduction

    Gliomas, glioneuronal tumours, and neuronal tumours

         Adult-type diffuse gliomas
              Astrocytoma, IDH-mutant
              Oligodendroglioma, IDH-mutant and 1p/19q-codeleted
              Glioblastoma, IDH-wildtype
         Paediatric-type diffuse low-grade gliomas
              Diffuse astrocytoma, MYB- or MYBL1-altered
              Angiocentric glioma
              Polymorphous low-grade neuroepithelial tumour of the young
              Diffuse low-grade glioma, MAPK pathway-altered
         Paediatric-type diffuse high-grade gliomas
              Diffuse midline glioma, H3 K27-altered
              Diffuse hemispheric glioma, H3 G34-mutant
              Diffuse paediatric-type high-grade glioma, H3-wildtype and IDH-wildtype
              Infant-type hemispheric glioma
         Circumscribed astrocytic gliomas
              Pilocytic astrocytoma
              High-grade astrocytoma with piloid features
              Pleomorphic xanthoastrocytoma
              Subependymal giant cell astrocytoma
              Chordoid glioma
              Astroblastoma, MN1-altered
         Glioneuronal and neuronal tumours
              Ganglioglioma
              Gangliocytoma
              Desmoplastic infantile ganglioglioma / desmoplastic infantile astrocytoma
              Dysembryoplastic neuroepithelial tumour
              Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters
              Papillary glioneuronal tumour
              Rosette-forming glioneuronal tumour
              Myxoid glioneuronal tumour
              Diffuse leptomeningeal glioneuronal tumour
              Multinodular and vacuolating neuronal tumour
              Dysplastic cerebellar gangliocytoma (Lhermitte-Duclos disease)
              Central neurocytoma
              Extraventricular neurocytoma
              Cerebellar liponeurocytoma
         Ependymal tumours
              Ependymal tumours: Introduction
              Supratentorial ependymoma
              Supratentorial ependymoma, ZFTA fusion-positive
              Supratentorial ependymoma, YAP1 fusion-positive
              Posterior fossa ependymoma
              Posterior fossa group A (PFA) ependymoma
              Posterior fossa group B (PFB) ependymoma
              Spinal ependymoma
              Spinal ependymoma, MYCN-amplified
              Myxopapillary ependymoma
              Subependymoma

Choroid plexus tumours

              Choroid plexus papilloma
              Atypical choroid plexus papilloma
              Choroid plexus carcinoma

Embryonal tumours

    Medulloblastoma

              Medulloblastoma: Introduction
         Medulloblastomas, molecularly defined
              Medulloblastoma, WNT-activated
              Medulloblastoma, SHH-activated and TP53-wildtype
              Medulloblastoma, SHH-activated and TP53-mutant
              Medulloblastoma, non-WNT/non-SHH
         Medulloblastomas, histologically defined
              Medulloblastoma, histologically defined

    Other CNS embryonal tumours

              Other CNS embryonal tumours: Introduction
              Atypical teratoid/rhabdoid tumour
              Cribriform neuroepithelial tumour
              Embryonal tumour with multilayered rosettes
              CNS neuroblastoma, FOXR2-activated
              CNS tumour with BCOR internal tandem duplication
              CNS embryonal tumour NEC/NOS

Pineal tumours

              Pineal tumours: Introduction
              Pineocytoma
              Pineal parenchymal tumour of intermediate differentiation
              Pineoblastoma
              Papillary tumour of the pineal region
              Desmoplastic myxoid tumour of the pineal region, SMARCB1-mutant

Cranial and paraspinal nerve tumours


              Cranial and paraspinal nerve tumours: Introduction
              Schwannoma
              Neurofibroma
              Perineurioma
              Hybrid nerve sheath tumours
              Malignant melanotic nerve sheath tumour
              Malignant peripheral nerve sheath tumour
              Cauda equina neuroendocrine tumour (previously paraganglioma)

Meningioma

              Meningioma

Mesenchymal, non-meningothelial tumours involving the CNS

              Mesenchymal, non-meningothelial tumours involving the CNS: Introduction

    Soft tissue tumours

         Fibroblastic and myofibroblastic tumours
              Solitary fibrous tumour
         Vascular tumours
              Haemangiomas and vascular malformations
              Haemangioblastoma
         Skeletal muscle tumours
              Rhabdomyosarcoma
         Tumours of uncertain differentiation
              Intracranial mesenchymal tumour, FET::CREB fusion-positive
              CIC-rearranged sarcoma
              Primary intracranial sarcoma, DICER1-mutant
              Ewing sarcoma

    Chondro-osseous tumours

         Chondrogenic tumours
              Mesenchymal chondrosarcoma
              Chondrosarcoma

    Notochordal tumours

              Chordoma

Melanocytic tumours

              Melanocytic tumours: Introduction
         Diffuse meningeal melanocytic neoplasms
              Diffuse meningeal melanocytic neoplasms: Melanocytosis and melanomatosis
         Circumscribed meningeal melanocytic neoplasms
              Circumscribed meningeal melanocytic neoplasms: Melanocytoma and melanoma

Haematolymphoid tumours involving the CNS

              Haematolymphoid tumours involving the CNS: Introduction

    Lymphomas

         CNS lymphomas
              Primary diffuse large B-cell lymphoma of the CNS
              Immunodeficiency-associated CNS lymphomas
              Lymphomatoid granulomatosis
              Intravascular large B-cell lymphoma
         Miscellaneous rare lymphomas in the CNS
              MALT lymphoma of the dura
              Other low-grade B-cell lymphomas of the CNS
              Anaplastic large cell lymphoma (ALK+/ALK−)
              T-cell and NK/T-cell lymphomas

    Histiocytic tumours

              Erdheim-Chester disease
              Rosai-Dorfman disease
              Juvenile xanthogranuloma
              Langerhans cell histiocytosis
              Histiocytic sarcoma

Germ cell tumours

              Germ cell tumours of the CNS

Tumours of the sellar region

              Tumours of the sellar region: Introduction
              Adamantinomatous craniopharyngioma
              Papillary craniopharyngioma
              Pituicytoma, granular cell tumour of the sellar region, and spindle cell oncocytoma
              Pituitary adenoma / pituitary neuroendocrine tumour
              Pituitary blastoma

Metastases to the CNS

              Metastases to the brain and spinal cord parenchyma
              Metastases to the meninges

Genetic tumour syndromes involving the CNS

              Genetic tumour syndromes of the nervous system: Introduction
              Neurofibromatosis type 1
              Neurofibromatosis type 2
              Schwannomatosis
              Von Hippel-Lindau syndrome
              Tuberous sclerosis
              Li-Fraumeni syndrome
              Cowden syndrome
              Constitutional mismatch repair deficiency syndrome
              Familial adenomatous polyposis 1
              Naevoid basal cell carcinoma syndrome
              Rhabdoid tumour predisposition syndrome
              Carney complex
              DICER1 syndrome
              Familial paraganglioma syndromes
              Melanoma-astrocytoma syndrome
              Familial retinoblastoma
              BAP1 tumour predisposition syndrome
              Fanconi anaemia
              ELP1-medulloblastoma syndrome

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